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How a simple brushing with a toothpaste can add an effect on Obesity induced Type 2 diabetes?

Thursday, November 25, 2010

Recently I read three articles, and when I linked them each other then I found it as interesting. The articles are,
a) Antibacterial components in the toothpaste.
b) Gut bacteria and their role in the absorption of undigested food materials in the gut.
c) Obesity induced Type 2 diabetes.
The first thing I noticed is, all the three topics are related with digestion, digestive tract and the gut.
Let me start with the topics first. Then I can summarize the three into a single point.
So here we are,
Toothpaste:  The common toothpastes we are using contain different kinds of chemicals like surfactants and anti bacterial agents. These chemicals are mainly used to remove the harmful bacteria so that the decay of the tooth can be prevented. There are a group of antibacterial agents present in the toothpaste. Stannous fluoride, Sodium monofluorophosphate, Hydrated silica, Polyethylene glycol, Polypropylene glycol, Sodium bicarbonate, Triclosan, Titanium dioxide are some of the examples. The combined action of these chemicals will prevent the activity of the bacteria in the mouth.
Gut bacteria: About 1000 trillion gut bacteria are present in the human gut. Most of them are needed for the digestion as well as absorption of different food forms. These microorganisms produce certain enzymes which is absent in the human body and so essential for the digestion of starch, fiber, oligosaccharides, and complex sugars. Almost 10% of the total gut microflora is consisted with a group of bacteria named Methanobrevibacter smithii, which ferment the complex sugar into simple absorptive molecules. If they are absent or less in number, the undigested carbohydrates and fats will not get absorbed by the body. That will result in Lactose tolerance, amylase deficiency, glucose-galactose malabsorption, sucrase-isosucrase deficiency.
Obesity induced Type 2 diabetes: Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on our health. Whenever in our body there is excess amount of sugar comes it will convert into stored fat. That is one of the cause of the Obesity. So as much as food digest and absorb in the gut will increase the amount of sugar and which will leads to excess fat deposition. Obesity can hinder the ability of the tissues throughout the body to respond properly to insulin. Such insulin resistance is a harbinger of a serious disease, Type 2 diabetes.
Summary: As usual this may be another foolish thinking from me.Once you brush your teeth using a toothpaste, a minute quantity of these chemicals will persist in our mouth even you had a perfect mouth wash. So once you drink or eat something just after the brushing, these chemicals will enter into the gut. As it is persistent in nature they will accumulate there for a long period. So everyday there will be an accumulation of these chemicals. As they have antibacterial effects that will start damaging the gut microflora. Once it start showing effect, there will be a reduction in the gut microflora. Especially bacteria like M.smithii. Which will lower the digestion of complex sugars and fat molecules into simple glucose/ energy forms. Then there will be a reduction in the excess glucose/ sugar molecules in the body. It will lowers the chance of forming stored fat in the body and will lower the complication of Obesity. Once the fat deposition stops, there will not be any hindrance for the insulin receptors. So there is a less chance of Obesity induced type 2 diabetes. 



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